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May improve mood and symptoms of depression - Vitamin B12 is needed for the production of serotonin, a chemical responsible for regulating mood

The modification adds a tyrosine residue at the N-terminus, creating a peptide that keeps the potent fat-burning properties of growth hormone while removing its unwanted effects on blood sugar, insulin sensitivity, and tissue growth

Oral vitamin B12 can also be taken as a sublingual tablet

The comparison between tirzepatide and next-generation triple agonists like retatrutide is relevant for researchers tracking the evolution of this field

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[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Nuzzo A., Czernichow S., Hertig A., Ledoux S., Poghosyan T., Quilliot D., Le Gall M., Bado A., Joly F