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Inhibition of intracerebral glioblastoma growth by targeting the insulin-like growth factor 1 receptor involves different context-dependent mechanisms

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Exercise stimulates mitochondrial biogenesis through PGC-1, nuclear respiratory factors (Nrf1 and Nrf2), and mitochondrial transcription factor A (TFAM), leading to enhanced energy metabolism and improved neuronal survival [253, 254]

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The role of the kidneys in determining circulating levels of these metabolites and the effect of these metabolites on renal function remain to be examined

Moreover, the chorionic gonadotropin (HCG) is a well-known and important biomarker present in the blood and urine of pregnant women, with pivotal roles against complications during prenatal care