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Figure 3: Photograph of Linus Pauling 1941 (credit: California Institute of Technology Yearbook) with a diagram of his instructionist theory

3.1.3 Inhibiting chemotaxis A different strategy to alleviate neutrophilic inflammation focuses on directly reducing the influx of neutrophils into affected tissues

10.1371/journal.pone.0077572 PLoS One 52 MarjaskaM.McCartenJ

DRI (2000) Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids

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Given the evidence that activation of the neuroendocrine stress axis can alter redox balance 15,55,56 , we speculate that an excessive release of glucocorticoids altered oxidative stress and antioxidant levels in the brain by increasing ROS production, leading to higher glutathione ratios and DNA damage 53