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10.1038/s41422-020-0332-7 Cell Res

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-catenin signaling in murine liver zonation and regeneration: a Wnt-Wnt situation
380,381 Loss of OPA1 disturbs the structure and integrity of the IMM, leading to the release of cytochrome c in a which is mainly sequestered within the tight cristae junctions
This increases susceptibility to infections, slows recovery from illness, and promotes chronic low-grade inflammation (42)