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2014, 15 (7), R89

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In this integrated manner, CoQ 10 limits the production of lipid peroxyl radicals and protects the circulating lipoproteins, the cellular membrane proteins, the mitochondrial DNA, and the ETC membranes [26,34,35,36]

Likewise, the XPC gene plays a crucial role in the NER pathway, encoding a protein essential for the recognition of damaged DNA

This precise targeting allows stubborn pigmentation to fade evenly and naturally over time

Fourth, ferroptosis biomarkers (e.g., MDA, 4-HNE, GPX4 activity) lack standardized protocols and sufficient specificity to distinguish ferroptosis from other oxidative stress or cell death forms, impeding patient stratification and treatment monitoring (114116)