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CGA prevents B16F10 melanoma cell proliferation by facilitating the tumor-associated macrophage (TAM) polarization from M2 to M1

The pellet was resuspended in 20 mL Trisbuffered saline containing 50 mm Tris and 150 mm NaCl at pH 7.6

The integration of omics data (e.g., transcriptomic, proteomic and metabolomic) into the risk assessment of chemical mixtures has great potential to reveal combined effects at a mechanistic level, providing insights into modes of action or adverse outcome pathways

M., Kamp, G

However, two studies reported an increase of 1 subunit mRNA expression (34, 64), one study revealed an increase of 5 subunit mRNA (34), one study observed an increase of the GABA A receptor 1 subunit protein (72), and one study demonstrated no change of the 4 receptor subunit (80)