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Through dysregulation, necroptosis in cancer can lead to tumor growth, inflammation, and immunological suppression, in addition to serving as a fallback mechanism when apoptosis is suppressed (Della Torre et al

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Compared with synthetic drugs, plant-derived compounds typically display lower intrinsic toxicity and achieve broad therapeutic effects through synergistic, multi-pathway regulationthat positions them as valuable lead structures for drug discovery (Mittal and Sharma, 2024)

10.2147/CPAA.S307464