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Output projections from the internal segment of the globus pallidus (GPi) and pars reticulata of the substantia nigra (SNpr) are modulated by two basal ganglionic circuits, which are referred to as the direct and indirect pathways

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A higher intake of flavonoidsparticularly anthocyanins found in berries, grapes, and red winehas been associated with a lower risk of developing PD in human cohort studies (9)

10.1016/S0014-827X(03)00193-9 [DOI] [PubMed] [Google Scholar] Cavaletti G., Marmiroli P

Elevated intracellular iron can saturate NMs binding sites, causing iron release from low-affinity sites and enhancing iron-driven oxidative stress (128)