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Melanogenesis and appetite suppression depend on cumulative receptor occupancy over days, not intraday plasma spikes

The HOMA-IR of the HFD group was 4.3-fold higher than the ND group, and normal in the G2000 group (Fig

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Casado-Vela J, Martinez-Esteso MJ, Rodrguez E, Borras E, Elortza F, Bru Martinez R: iTRAQ-based quantitative analysis of protein mixtures with large fold change and dynamic range