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& Abu Bakar, F
My completely biased (but data-backed) answer: start with AOD 9604

Caspase inhibition causes hyperacute tumor necrosis factorinduced shock via oxidative stress and phospholipase A2

Int J Mol Sci (2018) 19:2729

Glucagon-producing neuroendocrine tumour associated with hypoaminoacidemia and skin lesions
137,138 ERS Continuous insulin production and secretion in cells under chronic hyperglycemia and IR result in the overload of protein folding machinery and the accumulation of excessive misfolded or unfolded proteins in the ER, therefore triggering UPR and the ERS
