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Mitochondrial antioxidant proteins in the first line of defense against ROS/RNS fall into three categories, including non-enzymatic antioxidants (i.e., GSH), direct enzymatic antioxidants (i.e., SOD2 and GPx), and indirect enzymatic antioxidants [i.e., glutathione reductases (GR), peroxiredoxins, and thioredoxins (Trx)] [96, 97]
Cell Rep 10(8):12691279
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2.2.2 Glycyrrhiza uralensis glycyrrhizic acid Glycyrrhizic acid (GA) alleviates oxidative stress via two synergistic mechanisms: inhibition of the HMGB1/TLR4/NF-B pathway and activation of the PI3K/Akt pathway
