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de Matos (PhD fellow sponsored by the PRC) University Utrecht, The Netherlands Abstract This project concerns the development of stimuli-responsive liposomes for the controlled release of therapeutic proteins, such as mistletoe lectin-I (ML-I)

Post-mortem studies of brains from patients with HD have shown increased levels of DA and increased activity of tyrosine hydroxylase (TH), the rate-limiting enzyme in DA synthesis, in the striatum and SNc 3,4,5
It seems highly unlikely that the various potential targets in cells show an equivalent sensitivity to specific ROS and thus there is likely to be a hierarchy for oxidation and functional change that is dependent on factors such as their location compared with the site of generation of the radical species, the nature of the oxidizing species, the local concentration of antioxidants, etc

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Outcome predictability of serum alkaline phosphatase in men with pre-dialysis CKD
