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J Biol Chem 286 , 1114111154, doi: 10.1074/jbc.M110.196543 (2011)

Users with metabolic syndrome or insulin resistance often see the earliest improvements

Supporting our understanding, there has been no case report dating back to 1965 documenting any allergic reaction of any related sulfate- or sulfite-related drug to patients with a history of a sulfa allergy

YH: Conceptualization, Formal Analysis, Methodology, Writing original draft

Although the protein is of mesophilic origin, optimal temperature for the enzyme activity is 60C

Data on collagen peptides in the joint context exists, with durations of several weeks to months depending on the studies