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The mechanisms underlying these potential synergistic effects remain under active investigation and may involve growth factor signaling, extracellular matrix synthesis, or anti-catabolic pathways in joint tissues

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As previously mentioned, inhibitors targeting NNMT often bear structural resemblance to one or both of its substrates

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(Liu is on scientific advisory board of the University of Oxfords Jenner Institute, which developed AstraZenecas vaccine for COVID-19.) Had this to say in The Scientist

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