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The discovery of 5amino1mq (5amino1methylquinolinium) originated from intensive research into metabolic disorder regulation, centered on the inhibition of nicotinamide Nmethyltransferase (NNMT)
doi:10.1007/s10815-015-0553-8
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In agreement with our hypothesis, the administration of TAT-DAT NT also rescues the hyperactivity, and improves spontaneous alternation behavior of spontaneously hypertensive rats (SHR) in a Y-maze, a commonly used animal model of ADHD
and Yamabe et al
