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Older Adults As we age, the bodys ability to absorb B12 from food decreases, making supplementation essential

This age-related NAD+ depletion impairs mitochondrial energy production, reduces SIRT1 activity, compromises DNA repair mechanisms, and accelerates cellular senescence

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Patients typically use it as part of a body-recomposition protocol alongside resistance training and nutrition

Resistance training helps preserve the muscle that keeps metabolism healthy, and steady protein intake supports that muscle, so the peptide becomes one part of a sustainable approach

2.1.1 Association between decreased levels of NAD + and MetS NAD + functions as a crucial coenzyme in cellular energy metabolism