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Activation of human platelet protein kinase C-2 in vivo in response to acute hyperglycemia

Lumigan (bimatoprost ophthalmic solution) is an FDA-approved medication widely prescribed to lower IOP in glaucoma patients

Das S, Kaur S

doi: 10.3389/fphar.2021.718147

Research demonstrates that BPC-157 upregulates vascular endothelial growth factor receptor-2 (VEGFR2) at both mRNA and protein levels in endothelial cells without increasing VEGF-A itself, instead sensitizing cells to existing VEGF signaling while simultaneously activating the Src-Caveolin-1-endothelial nitric oxide synthase (eNOS) pathway

This mast cell dysfunction perfectly explains why patients wonder what causes Long COVID symptoms to flare so violently after eating