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Notably, at physiological concentrations, TMAO can enhance the integrity of the bloodbrain barrier through the tight junction regulator annexin A1, limit the reactivity of astrocytes and microglia, and protect the cognitive function of mice from inflammatory challenges

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Possible side effects include abdominal pain and bloating, diarrhea, and gout

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I do not recall his normal checks of my thyroid, or anything else. Magness, who had been a patient of Browns since he was a top high school distance runner, said that the apparent alterations may have been added to make it look like the infusion was conducted alongside a thorough exam

Journal of cerebral blood flow and metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism , 271678X17746186 (2017)