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We and others have demonstrated that dopaminergic cell death associated with PD-risk factors (genes and environmental exposures) is mediated by a dysfunction in both bioenergetics and redox homeostasis coupled to alterations in central carbon metabolism

Cell 181 (2), 271-280.e8 (2020b)

People deficient in vitamin B12 may only experience some of these symptoms or a few in combination

[DOI] [PubMed] [Google Scholar] 66.Ichijo H., Nishida E., Irie K., ten Dijke P., Saitoh M., Moriguchi T., Takagi M., Matsumoto K., Miyazono K., Gotoh Y

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[DOI] [PMC free article] [PubMed] [Google Scholar] 35.van der Merwe JQ, Hollenberg MD, MacNaughton WK