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Technical triplicates were used for each sample and the quantified RNA normalized against TBP (human) or Hprt (mouse) as housekeeping transcripts (Supplementary Tables 9 and 10)

The question isn't whether levels decline it's whether yours have declined enough to cause symptoms

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10.1002/biof.1815 7 BarnesM

If enough axons are injured in this way, then the ability of nerve cells to integrate and function may be lost or greatly impaired

Decreased scavenge and increased formation of cytokines activates naive neutrophils, causing a feed-forward loop of excessive inflammation in diabetes [17, 18]