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Therefore, as in the case of ROS, low and regulated production of NO is associated with paracrine signaling processes whereas its overproduction can cause damage to biological macromolecules and determine many pathological states [18,23,35]

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10.1016/j.jjcc.2014.02.001 30 FrederickD

doi: 10.1016/j.ijpharm.2023.123271

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