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Another plausible explanation is that ROS at low levels regulate signaling to control physiological processes and adaptation to stressful conditions and, thus, antioxidants might interfere with our body's way to deal with stressful conditions

Its a free radical generated during oxygen reduction and can signal for immune responses but also contribute to stress if not managed

doi: 10.1002/tox.23124

Nielsen, T
Bhatti JS, Sehrawat A, Mishra J, Sidhu IS, Navik U, Khullar N, et al

The mechanism behind this may be due to improved chromatin accessibility and the transcriptional regulatory network
