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Persistent mitochondrial ROS generation leads to lipid peroxidation, increased membrane permeability, mitochondrial uncoupling, and inflammatory signalling via tumor necrosis factor-alpha (TNF-), thereby perpetuating hepatocellular damage [55, 56]
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HodgsonJMPuddeyIBCroftKDBurkeVMoriTACaccettaRAet al
96: 235660 Wu X, Huang W, Prasad PD, et al
