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Description
The relevance of this incomplete list is to highlight that irreversible inactivation, rather than reversible regulation, can occur through the reaction of the same redox-activated control motifs (cystine thiol(ate) residues) with EdAG, rather than with the physiologically appropriate actuator (glutathione sulphinate, glutathione disulphide)

Microbiota-gut-brain axis in neurodegenerative diseases: molecular mechanisms and therapeutic targets

Aucune contre-indication connue pour le glutathion
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In experimental studies, MOTS-c has demonstrated protective effects on blood vessels

[DOI] [PubMed] [Google Scholar] 47.Vyunova T, Andreeva L, Shevchenko K, Myasoedov N: Peptide-based anxiolytics: The molecular aspects of heptapeptide selank biological activity

ALS-related mutant SOD1 aggregates interfere with mitophagy by sequestering the autophagy receptor optineurin