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The first was to identify a set of rules or chemical space/pKa ranges where these two tools were most concordant with DataWarrior pKa values
The peptide chelates divalent copper with high affinity, and the bound complex has been the subject of work on wound healing, hair follicle stimulation, anti-inflammatory effects in the skin, and a broad set of downstream gene expression changes related to collagen synthesis and extracellular matrix remodeling

The Bioavailability Hurdle: Here's the catch, though

Copper peptide serums offer a unique advantage in this respect because they represent a category that is both scientifically recognizable and commercially flexible

10.1073/pnas.1121251109 51 Kuboshima-AmemoriS.SawaguchiT
