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However, in the greatest majority of the cell lines ionotropic glutamate receptors are present, co-existing to CySS/glutamate antiporters and metabotropic glutamate receptors, supporting the assumption that excitotoxicity effect in these cells is accumulative

Expert Clinical Visual Grading: An independent trained evaluator assessed hyperpigmentation severity and skin tone evenness under standardised conditions at both timepoints, using a validated PCR clinical grading scale

2009, 296 (6): L888-900

294 Phase 1 and Phase 2a, First-in-human Study of DRP-104, a Glutamine Antagonist, in Adult Patients With Advanced Solid Tumors (2020)

Also, in the case of 3D cultures, Western blotting analysis demonstrated that angiotensin-converting enzyme and CD40 were upregulated, and that sirtuin 1 and sirtuin 6 were inhibited after TNF- treatment