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In the context of stroke, the accumulation of AGEs may contribute to vascular dysfunction and exacerbate the damage caused by the initial ischemic event [105]

Inhibition by VopS is believed to be a result of AMPylation of the RhoGTPase Rac by this effector, effectively blocking it from interacting with other members of the NADPH oxidase complex (Woolery et al., 2014)

As a result, there was an increase in blood vessel density observed in both the ischemic and non-ischemic myocardial tissue

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In the context of gastric cancer, GPNA inhibits Gln uptake by targeting SLC1A5, thereby enhancing the anti-tumor effects of cetuximab both in vivo and in vitro ( 99)

Innate immunity is the bodys first defense against invading pathogens and comprises several types of cells, such as macrophages, neutrophils, and dendritic cells