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The GHK sequence also appears within the alpha-2(I) chain of type I collagen, leading to the hypothesis that collagen degradation at wound sites releases GHK fragments that then bind copper and signal for new collagen production, creating a self-repair feedback loop

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For example, circulating GLP-1 concentrations are low and postprandial increases are minimal (11)

Barrier and texture improvements appear within 2 to 4 weeks

BMJ 2010;340:c365