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For inflammatory diseases such as pulmonary disorders, developing inhalable formulations may achieve higher drug concentrations at target sites

Inhibition of Mettl3-mediated m6a rna modification of Hmgcs1 protects retinal ganglion cells from glutamate excitotoxicity-induced ferroptosis in a rat model of glaucoma

10.1128/IAI.67.10.5170-5175.1999 138

The cells are quite literally starved of the biochemical currency they need to function, leading to widespread systemic exhaustion and a failure to recover from even minor physical or cognitive exertion