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The breadth of documented activity reflects what the original investigators have described as systems-level pharmacology: rather than acting through a single high-affinity receptor, BPC-157 appears to modulate multiple intersecting cellular pathways including nitric oxide signalling, growth-factor receptor expression, dopamine and serotonin metabolism, and angiogenic vessel formation

J Pediatr Endocrinol Metab

Yadav et al., 2022[156]

The Providence/Microsoft team also developed TRIALSCOPE, an AI framework that merges real-world evidence, clinical genomics and treatment data to predict or replicate trial results, aiding faster therapy development

Continuous use is not the intended approach

Subcutaneous injection near injury sites may provide localized benefit, though BPC-157 also migrates systemically to damaged tissues from any injection location