glutathione synthetase deficiency peripheral smear 💐Megaloblastic Anemia (Folate, Vitamin B12 Deficiency) 💐 💐 Clinical Features💐 ✓Vitamin B12 deficiency: Neurological manifestations due to spinal cord involvement, such as difficulty maintaining posture and paresthesia in hands and feet ✓Folate G6PD Deficiency - Hematology -

Overall, EGCG emerges as a promising natural compound with the capacity to combat chronic neuroinflammation and oxidative stress, offering novel avenues for the development of neuroprotective strategies in the treatment of neurodegenerative disorders

doi: 10.1038/s41586-020-1969-6

In babies and young children, this barrier is still developing, which makes it more vulnerable to becoming leaky. Factors contributing to leaky gut include: Food Allergies and Sensitivities : Common triggers like dairy, soy, eggs, and gluten can irritate the gut lining

10.1007/s11914-012-0098-z 64

10.3390/antiox10030383 5 ChangY.JeongS

First, under normal conditions, elevated HO1 expression attenuates oxidative stress to exert cytoprotective effects, and second, sustained HO1 upregulation releases ferrous iron to exacerbate oxidative stress, which leads to ROS accumulation through the Fenton reaction