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T-2 toxin and its cardiotoxicity: New insights on the molecular mechanisms and therapeutic implications

Co-treatment with a specific inhibitor of the lactate/H + transporter MCT1, AZD3965, led to increased apoptosis in APAP-treated cells, suggesting that lactate accumulation could be a cause of cell death in this model

Study approval All the experiments were developed according to relevant guidelines and regulations

doi: 10.1073/pnas.1017213108 126 Ushio-FukaiMAlexanderRW

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