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4.3.3 Gut microbiota disorder The microbial community in the human gastrointestinal tract has been shown to be involved in a variety of physiopathological processes in the gut, and a unique gut microbiome signature exists for NAFLD (Vallianou et al., 2021)

Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, and Impairment of Fertility Valproate was administered orally to rats and mice at doses of 80 and 170 mg/kg/day (less than the maximum recommended human dose on a mg/m2 basis) for two years

doi: 10.1016/j.bbi.2018.07.017 114 SuF.BaiF.ZhangZ

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Benedini, S., Perseghin, G., Terruzzi, I., Scifo, P., Invernizzi, P