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Possible B12 injection side effects tend to be mild and short-lived, and may include: Injection site pain, redness, or swelling Mild itching Brief diarrhea (less common) A feeling of warmth after the injection Serious side effects are rare

What to expect during the procedure and recovery Pain management specialists use imaging to guide the needle to the area that surrounds the nerve

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Journal of Hepatology 50 , 11841191, doi: 10.1016/j.jhep.2009.01.030 (2009)