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Induced pluripotent stem cells derived from individuals with FXS have been shown to exhibit delayed GABA polarity conversion, reduced numbers of GABAergic inhibitory interneuron populations, and hyperexcitable membrane properties
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As a result, hydrophobic molecules such as aromatic amino acids, long-chain alkyl amino acids, and certain lipids act as natural self-assembling substances
Lancet 1:155, 1977
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