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Other indications include malabsorption disorders (such as Crohn's disease or coeliac disease), following gastric surgery, strict vegan diets without supplementation, and certain medications that interfere with B12 absorption

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Vitamin B12 deficiency results in the dysfunction of numerous systems, including the central nervous system [1]

For example, hepcidin-like molecules have been shown to ameliorate iron overload in preclinical models of HH and -thalassemia and are ongoing clinical evaluation

This treatment restored NAD + levels, improving mitochondrial function 164

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