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1,3-Butanediol attenuates hypertension and suppresses kidney injury in female rats

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In particular, an RCT including 108 diabetic patients with mildmoderate ED demonstrated that a daily treatment with 5 g l-ARG plus 10 mg tadalafil, administered for 8 weeks, significantly improved ED assessed by IIEF-5 and testosterone levels, with a more significant improvement in both endpoints compared to patients receiving tadalafil or l-ARG as single compounds, whereas the significant improvements at basal and dynamic PDU were similar between groups [16]

HbA1c, which reflects average blood sugar over 2-3 months, dropped by up to 2.5 percentage points

*Correspondence: Liu Heng, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers