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Increased levels of IL-1, IL-6, and TNF- further demonstrated systemic immune activation (Yang J.-Z

Apoptosis 19, 10991112

Notably, the focus on healthy males may have limited the observation of significant biochemical changes, highlighting the need for further research in more diverse populations

When a patient required a fluid bolus, 500 mL of normal saline were administered and several hemodynamic parameters were recorded continuously: cardiac output (CO), arterial pressure (AP), mean systemic pressure (P ms )

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We classified potential contaminants and sparse OTUs based on known culturing results, curated data collections, and documented contaminants specific to reagents or laboratories (Salter et al., 2014