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Description
Kupffer cells, the resident macrophages of the liver, and monocyte-derived macrophages have both been implicated as cells that both contribute to the injury and are critical for regeneration

The effectiveness of glutathione depends on its state within the cell
The rate constant for the reaction between ascorbic acid and superoxide (at pH 7.4) using the xanthinexanthine oxidase system was estimated to be 5.4 10 6 M 1 s 1 (Som et al

Nanotechnology 33 , 062004 (2021)

Therefore, the reduced Hcy levels observed in this study could have led to an upregulation of the enzyme, thereby increasing glutathione synthesis [33]

These results indicate that they are excellent candidates as bioactive dressings for cutaneous skin wound healing
