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This epidemic preceded all others by three decades and its features are consistent with widespread unsafe needle practices at the beginning of the 20 th century and contaminated blood transfusions which stopped only after the discovery of HCV in 1989 and the subsequent screening of all blood donations for HCV 67,68

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Enriched with Vitamin C, this lip therapy helps brighten dull lips while restoring their natural softness

Clinical photo of an irregularly shaped, tan-brown macule in the right side of the posterior hard palate

The Montreal cohort is supported by grants from the National Institutes of Health (NIH) U19AI159819 and the Canadian Institutes of Health Research (CIHR) (PJT-173467) to N.S