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Removal of Ca2+ by the addition of EGTA or application of Ca2+-channel blockers, verapamil, diltiazem, and Ni2+, inhibited the BK-induced IP accumulation and Ca2+ mobilization, indicating that Ca2+ influx was required for the BK-induced responses

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Fair-skinned people with signs of actinic skin damage (actinic keratoses and solar lentigines) and nonmelanoma skin cancer have been linked to a higher risk of LM and LMM [8, 9]