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This review summarizes the current knowledge of the emerging role of neutrophils in the context of chronic inflammation

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endocytosis and formation of peroxisomes), there was no corresponding increase in genes related to ROS metabolism

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GHK-Cu exerts its effects primarily through gene expression modulation, influencing approximately 31% of the human genome by upregulating genes involved in antioxidant responses, DNA repair, protein metabolism, and cellular growth while downregulating inflammatory mediators, fibrinogen synthesis, and pathological processes including cancer metastasis