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The density of astrocytes expressing the disrupted-in-schizophrenia 1 (DISC1) gene has been reported to be decreased in the dentate gyrus of hippocampus in schizophrenia patients compared to healthy controls [71]

TNF- or TNF-R1 knockout animals have reduced liver injury after APAP administration, suggesting that TNF- exerts a toxic effect [219,220,221,222,223]

Overexpression of FSP1 in GPX4 knockout cells can also significantly reduce phospholipid peroxidation products, thereby inhibiting the occurrence of ferroptosis, demonstrating that the anti-ferroptosis effect of FSP1 does not depend on the expression of GPX4

As cells age, CAT forms a tetrameric molecule in the cytosol and remains inactive

Geibel, M

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