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Individuals with genetic changes in the ABCG5 and ABCG8 genes tend to absorb more plant sterol, with the most extreme cases diagnosed as sitosterolemia

Figure 5: Representative photographs of rat liver by light microscope with H&E staining at 400X magnification

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For cardiovascular or other health benefits, dividing the daily amount into 2-3 doses may be more effective due to L-arginine's relatively short half-life