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Taken together, these findings suggest that NSBSO-induced GSH depletion and synthesis inhibition can elevate intracellular ROS, thereby activating the caspase family, leading to GSDME cleavage and cell pyroptosis
Oxidative stress that leads to inflammation is a crucial contributor to the progression of liver damage
May influence gene expression , promoting cellular repair, reducing oxidative stress, and restoring extracellular matrix integrity
Artemisinin derivatives: toxic for laboratory animals, safe for humans
Ketogenic diet ameliorates axonal defects and promotes myelination in PelizaeusMerzbacher disease
Cochrane Handbook for Systematic Reviews of Interventions, 205-228
