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As per Base Ball Founders by Peter Morris et

Deficiency in vitamin B12 can lead to the accumulation of methylmalonyl-CoA, which is subsequently converted to methylmalonic acid (MMA) (, , )

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Its broad benefitsranging from bone strength and immune resilience to mood balance and hormonal regulationmake it one of the most valuable therapies in preventive and functional medicine

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These two physicians initially studied patients with pernicious anemia and suspected that patients with this type of anemia had a deficiency in nutrients