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This represents a potential caveat for the translation of preclinical into clinical research, which is further emphasized by the well-documented differences in responses to medication across ALS phenotypes (164)

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Marginal zone and B1 B cells as part of a natural immune memory

10.1038/s41598-019-55473-4 62 GiloteauxL.LiJ.HornigM.LipkinW

Although a large number of serotypes have been identified, the most extensively investigated is the serotype AAV2
