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local anesthetic applied Injection Points: Typically include the AC joint capsule and coracoclavicular ligament attachments Solution Used: 15-25% dextrose + 1% lidocaine or procaine Guidance: Can be done freehand or under ultrasound guidance for precision Post-Injection Care Mild soreness or swelling is expected for 13 days Avoid anti-inflammatory medications (they may blunt the desired response) Gentle range of motion exercises encouraged Physical therapy may be added at any time Treatment Frequency Prolotherapy is typically performed every 34 weeks 36 sessions are usually recommended depending on severity and how you are progressing Clinical Evidence Supporting Prolotherapy for AC Joint Injury While large randomized controlled trials are limited for AC separation specifically, prolotherapy has demonstrated efficacy in multiple musculoskeletal conditions involving ligament and joint instability: Rabago et al

10.3390/ijms22158180 [DOI] [PMC free article] [PubMed] [Google Scholar] 315.Srinivasan K, Pandey AK, Livingston A, Venkatesh S

Treatments take about 1520 minutes , are extremely well tolerated, and often produce noticeable improvements in vitality within 24 hours

Storage and Shelf Life: Proper storage of TB-500 nasal spray is important to maintain its potency

[DOI] [PubMed] [Google Scholar] 33.Chakravarti S, et al

Because its administered intravenously, the nutrients bypass the digestive system, allowing for higher concentrations to reach the cells quickly and efficiently