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The action of this oxoferryl porphyrin radical on tyrosine 385 creates a tyrosyl radical that abstracts a bis -allylic hydrogen and forms a conjugated radical

Both osteopontin and sclerostin exhibit potential as novel biomarkers for neurodegenerative diseases (74)

Additional proposed mechanisms include interaction with NMDA receptors and modulation of the stress and HPA axis , the hypothalamic-pituitary-adrenal system that governs the body's stress response

[7] Kwon, D

Moderate traumatic brain injury causes acute dendritic and synaptic degeneration in the hippocampal dentate gyrus

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