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Safely removing senescent cells is one of three approaches scientists are looking at in this area, alongside preventing cell damage in the first place, and stimulating stem cells to improve tissue regeneration once the senescent cells are cleared out

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To purify the fusion proteins, the GST-tagged and His-tagged Trx21 proteins were purified separately using the Glutathione Sepharose 4B system (GE Healthcare) and the His GraviTrap system (GE Healthcare), respectively, according to the manufacturers instructions